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The transmission dynamic of different hepatitis B-infected individuals with the effect of hospitalization
Authors:Tahir Khan
Affiliation:Department of Mathematics, University of Malakand, Chakdara, Khyber Pakhtunkhwa, Pakistan
Abstract:We propose an epidemic model for the transmission of hepatitis B virus along with the classification of different infection phases and hospitalized class. We formulate the model and discuss its basic mathematical properties, e.g. existence, positivity, and biological feasibility. Exploiting the next generation matrix approach, we find the basic reproductive number of the model. We perform sensitivity analysis to illustrate the effect of various parameters on the transmission of the disease. We investigate stability of the equilibria of the model in terms of the basic reproduction number. Conditions for the stability of the proposed model are obtained using various approaches. Finally, we perform the numerical simulations to discuss sensitivity analysis and to support our analytical work.
Keywords:Mathematical modelling  different phases of hepatitis B  hospitalization  basic reproduction number  sensitivity analysis  stability analysis  numerical simulation
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