Taxonomic colouring of phylogenetic trees of protein sequences |
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| Authors: | Gareth Palidwor Emmanuel G Reynaud Miguel A Andrade-Navarro |
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| Affiliation: | (1) Ontario Genomics Innovation Centre, Ottawa Health Research Institute, 501 Smyth, Ottawa, ON, K1H 8L6, Canada;(2) European Molecular Biology Laboratory (EMBL), Cell Biology and Biophysics Programme, Meyerhofstrasse 1, 69117 Heidelberg, Germany;(3) Department of Cellular and molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Canada |
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| Abstract: | Background Phylogenetic analyses of protein families are used to define the evolutionary relationships between homologous proteins. The
interpretation of protein-sequence phylogenetic trees requires the examination of the taxonomic properties of the species
associated to those sequences. However, there is no online tool to facilitate this interpretation, for example, by automatically
attaching taxonomic information to the nodes of a tree, or by interactively colouring the branches of a tree according to
any combination of taxonomic divisions. This is especially problematic if the tree contains on the order of hundreds of sequences,
which, given the accelerated increase in the size of the protein sequence databases, is a situation that is becoming common. |
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