Changes in the pituitary and hypothalamic content of methionine-enkephalin during the estrous cycle of rats |
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Authors: | MSA Kumar CL Chen TF Muther |
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Institution: | 1. Department of Reproduction, College of Veterinary Medicine, University of Florida, Gainesville Florida 32610, USA;2. Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, USA |
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Abstract: | Met-Enkephalin content of the anterior hypothalamic-preoptic area, medial basal hypothalamus, anterior pituitary, intermediate and posterior pituitary was measured using a specific radioimmunoassay. Met-Enkephalin content of the anterior hypothalamic-preoptic area, medial basal hypothalamus and anterior pituitary was very high on the morning of proestrus but decreased on the afternoon of proestrus and on estrus. The content of met-Enkephalin was more variable in the anterior pituitary than in the anterior hypothalamic-preoptic area and medial basal hypothalamus during the estrous cycle. The results suggest that the met-Enkephalin may be involved in regulating the hypothalamo-hypophyseal function during estrous cycle in the rat. |
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Keywords: | To whom reprint requests should be addressed |
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