| 霍乱弧菌群体感应系统影响生物膜形成的研究进展 |
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| 引用本文： | 叶晓敏,陆春. 霍乱弧菌群体感应系统影响生物膜形成的研究进展[J]. 微生物学杂志, 2010, 30(1): 80-83 |
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| 作者姓名： | 叶晓敏 陆春 |
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| 作者单位： | 中山大学,附属第三医院,广东,广州,510630 |
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| 摘 要： | 群体感应(quorum sensing,QS)是指细胞感知周围同类细胞的多寡或密度并调控基因表达的系统,它对大多数细菌的生物膜形成至关重要。目前对霍乱弧菌的QS系统已有较深入的研究,该菌的群体感应系统通过HapR、LuxO等多种信号分子调控生物膜的形成及消散。干扰QS系统将成为治疗生物膜相关感染的新方向。
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| 关 键 词： | 生物膜 群体感应 霍乱弧菌 |
Advance in Quorum-Sensing System to Affect Vibrio cholerae Biofilm Formation |
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| YE Xiao-min,LU Chun. Advance in Quorum-Sensing System to Affect Vibrio cholerae Biofilm Formation[J]. Journal of Microbiology, 2010, 30(1): 80-83 |
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| Authors: | YE Xiao-min LU Chun |
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| Affiliation: | YE Xiao-min,LU Chun (The Third Affil.Hosp.of Sun Yat-sen Uni.,Guangzhou 510630) |
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| Abstract: | Quorum sensing (QS) is a system to detect the surrounding amount of similar cell and to regulate gene expression,it is of very vital importance to the biofilm formation of most bacteria.At present,QS system of Vibrio cholerae has been thoroughly studied.Its QS system regulates the biofilm formation and dissipation through HapR,LuxO and other multiple signaling molecules.Interfering with QS system will become a new direction to treat biofilm correlated infection. |
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| Keywords: | biofilm quorum sensing Vibrio cholerae |
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