(1) Pain Management and Research Centre, Dept. of Anesthesiology, *Dept. of Clinical Epidemiology and Medical Technology Assessment, Dept. of Neurology, University Hospital Maastricht, Maastricht, The Netherlands
Abstract:
Background
Complex Regional Pain Syndrome type one (CRPS I) or formerly Reflex Sympathetic Dystrophy (RSD) is a disabling syndrome, in which a painful limb is accompanied by varying symptoms. Neuropathic pain is a prominent feature of CRPS I, and is often refractory to treatment. Since gabapentin is an anticonvulsant with a proven analgesic effect in various neuropathic pain syndromes, we sought to study the efficacy of the anticonvulsant gabapentin as treatment for pain in patients with CRPS I.