首页 | 本学科首页   官方微博 | 高级检索  
     

三七环二肽成分和人参内酰胺成分
引用本文:谭宁华,王双明,杨亚滨,何敏. 三七环二肽成分和人参内酰胺成分[J]. 云南植物研究, 2003, 25(3): 366-368
作者姓名:谭宁华  王双明  杨亚滨  何敏
作者单位:1. 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,云南,昆明,650204
2. 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,云南,昆明,650204;天津天士力制药集团有限公司药物研究所,天津,300142
基金项目:This work was supported by grants from the National Natural Science Fundation of China (39500182) and Natural Science Fund of Yunnan Province (95C088Q)
摘    要:From the roots of Panax notoginseng fourteen cyclodipeptides 1-14 were isolated including one new compound (1),seven new natural compounds (4-10) and six known compounds (2-3,11-14) together with one known other compound 15.The chemical structure of 1 was elucidated as cyclo-(Leu-Thr) based on spectral methods.From the roots of Panax ginseng five known lactams (16-20) includingpyrng lutamic acid were isolated together with butyric diacid,daucosterol and sucrose.The primary binactivity test showed that pyroglutamic acid and its n-butyl derivative have weak Ca^2 antagonistic activity.

关 键 词:三七 人参 五加科 环二肽 内酰胺
文章编号:0253-2700(2003)03-0366-03
修稿时间:2002-11-03

Cyclodipeptides of Panax notoginseng and Lactams of Panax ginseng
TAN Ning-Hua,WANG Shuang-Ming ,,YANG Ya-Bin,HE Ming. Cyclodipeptides of Panax notoginseng and Lactams of Panax ginseng[J]. Acta Botanica Yunnanica, 2003, 25(3): 366-368
Authors:TAN Ning-Hua  WANG Shuang-Ming     YANG Ya-Bin  HE Ming
Affiliation:TAN Ning-Hua1,WANG Shuang-Ming 1,2,YANG Ya-Bin1,HE Ming1
Abstract:From the roots of Panax notoginseng fourteen cyclodipeptides 1-14 were isolated including one new compound (1),seven new natural compounds (4-10) and six known compounds (2-3,11-14) together with one known other compound 15.The chemical structure of 1 was elucidated as cyclo-(Leu-Thr) based on spectral methods.From the roots of Panax ginseng five known lactams (16-20) including pyroglutamic acid were isolated together with butyric diacid,daucosterol and sucrose.The primary bioactivity test showed that pyroglutamic acid and its n-butyl derivative have weak Ca 2+ antagonistic activity.
Keywords:Panax notoginseng  Panax ginseng  Araliaceae  cyclodipeptides  lactams  
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号