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A common structural scaffold in CTD phosphatases that supports distinct catalytic mechanisms |
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| Authors: | Tirso Pons Ida Paramonov César Boullosa Kristina Ibáñez Ana M. Rojas Alfonso Valencia |
| Affiliation: | 1. Structural Biology and BioComputing Programme, Spanish National Cancer Research Centre (CNIO), , Madrid, Spain;2. Institute of Predictive and Personalized Medicine of Cancer (IMPPC), , Badalona, Spain;3. Life Sciences Department, Barcelona Supercomputing Center (BSC), , Barcelona, Spain |
| Abstract: | |
| Keywords: | structure comparison RNA polymerase II carboxyl‐terminal domain protein phosphatases catalytic mechanism HAD superfamily prolyl cis/trans isomerization oxidative stress neurodegeneration mental disorders Alzheimer's disease Parkinson's disease schizophrenia |