Genetic variations of insulin-like growth factor I in Italy |
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Authors: | R Palmarino E Mantuano P Lucarelli |
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Affiliation: | Centro di Genetica Evoluzionistica del CNR, Università La Sapienza, Roma, Italia. |
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Abstract: | Four Italian populations were examined for a HindIII RFLP associated with the human insulin-like growth factor I gene. No differences were observed among the four samples. The allele frequencies in Italy were: IGF-I HF = 0.834; IGF-I HS = 0.166. The polymorphism appears to be due to a 400-bp sequence insertion-deletion mechanism. |
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