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Binding of the MLL PHD3 Finger to Histone H3K4me3 Is Required for MLL-Dependent Gene Transcription
Authors:Pei-Yun Chang  Catherine A. Musselman  Alex Kuo  Tatiana G. Kutateladze
Affiliation:1 Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
2 Department of Pharmacology, University of Colorado-Denver School of Medicine, Aurora, CO 80045, USA
3 Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
Abstract:
Keywords:MLL, mixed-lineage leukemia   PHD, plant homeodomain   H3K4me3, H3 trimethylated at lysine 4   GST, glutathione S-transferase   ChIP, chromatin immunoprecipitation   HSQC, heteronuclear single quantum coherence   NOESY, nuclear Overhauser enhancement spectroscopy
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