1. Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Virchowstr. 179, 45147 Essen, Germany;2. Department of Hematology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany;3. Department of Hematology, Oncology and Hemostasiology, University Hospital Leipzig, University of Leipzig, Johannisallee 32A, 04103 Leipzig, Germany