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Structure and Mechanism of a Nitrate Transporter
Authors:Hanchi Yan  Weiyun Huang  Chuangye Yan  Xinqi Gong  Sirui Jiang  Yu Zhao  Jiawei Wang  Yigong Shi
Institution:1. Ministry of Education Key Laboratory of Protein Science, Tsinghua University, Beijing 100084, China;2. State Key Laboratory of Bio-membrane and Membrane Biotechnology, Tsinghua University, Beijing 100084, China;3. Tsinghua-Peking Joint Center for Life Sciences, Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China
Abstract:
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  • Highlights? Structure of the nitrate transporter NarU in substrate-free and -bound states ? Distinct conformations of NarU in substrate-free and -bound states ? Identification of a substrate binding site and transport path ? Transport mechanism may deviate from the rocker-switch model
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