1. Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA;2. Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA
Abstract:
Highlights? Human CD35, like CD21, binds EBVgp350/220, the major virion envelope glycoprotein ? CD35 mediates latent EBV infection when the fusion coreceptor HLA II is expressed ? Temperature, tempo, structure, and regulation distinguish CD35-mediated infection ? CD35 is a physiologically relevant EBV receptor