Expression of Genes Encoding the RhtB Family Proteins Depends on the Global Regulator Lrp

In this work, we continued to study the genes encoding the RhtB family proteins. We studied regulation of four genes of this family: rhtB, rhtC, yeaS, and yahN, two of which (rhtB and rhtC) were previously shown to be involved in amino acid efflux from cells. The results of this study showed that the expression of these genes is regulated by the global regulator Lrp; it depends on the presence of certain amino acids in the growth medium and increases in certain types of physiological stress.__________Translated from Molekulyarnaya Biologiya, Vol. 39, No. 3, 2005, pp. 374–378.Original Russian Text Copyright © 2005 by Kutukova, Zakataeva, Livshits.