The gene for human complement component C9 mapped to chromosome 5 by polymerase chain reaction |
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| Authors: | C Abbott L West S Povey S Jeremiah Z Murad R DiScipio G Fey |
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| Institution: | MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London, United Kingdom. |
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| Abstract: | The gene for human complement component C9 has been mapped to chromosome 5. This was achieved by using a novel application of the polymerase chain reaction to amplify specifically the human C9 gene on a background of rodent DNA in somatic cell hybrids. The assignment to chromosome 5 was confirmed by in situ hybridization to human metaphase chromosomes, giving a regional localization of 5p13. |
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