| 冷诱导细胞凋亡及其调控机制 |
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| 引用本文： | 叶岚,郑科,傅宇,万白羽,童微星,胡献明,朱睦元.冷诱导细胞凋亡及其调控机制[J].细胞生物学杂志,2006,28(4):551-555. |
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| 作者姓名： | 叶岚 郑科 傅宇 万白羽 童微星 胡献明 朱睦元 |
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| 作者单位： | 浙江大学生命科学学院 杭州310012(叶岚，郑科，傅宇，万白羽，朱睦元)，浙江大学宁波理工学院 宁波315100(童微星)，衢州职业技术学院 衢州324000(胡献明) |
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| 基金项目： | 国家自然科学基金资助项目(No.30370876)~~ |
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| 摘 要： | 冷和细胞凋亡有着密切的关系,冷诱导细胞凋亡的研究已经成为器官移植医学领域里的热点。冷诱导细胞凋亡的信号转导过程错综复杂,细胞内活性氧自由基、Ca2 、Fe2 以及冷相关基因都介导或调控冷引起的细胞凋亡。结合有关冷和细胞凋亡方面的研究进展,综述了与冷引起的细胞凋亡相关的信号转导过程和相关基因的调控机制。
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| 关 键 词： | 冷 细胞凋亡 活性氧 调控 信号转导 |
| 收稿时间： | 2005-11-10 |
| 修稿时间： | 2006-03-14 |
Cold-induced Apoptosis and Its Modulation Mechanism |
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| Lan Ye,Ke Zheng,Yu Fu,Bai-Yu Wan,Wei-Xing Tong,Xian-Ming Hu,Mu-Yuan Zhu.Cold-induced Apoptosis and Its Modulation Mechanism[J].Chinese Journal of Cell Biology,2006,28(4):551-555. |
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| Authors: | Lan Ye Ke Zheng Yu Fu Bai-Yu Wan Wei-Xing Tong Xian-Ming Hu Mu-Yuan Zhu |
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| Institution: | 1College of Life Sciences, Zhejiang University, Hangzhou 310012, China;2Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, China; 3Quzhou College of Technology, Quzhou 324000, China |
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| Abstract: | Cold and apoptosis are tightly correlated and the research on cold-induced apoptosis has become a hotspot within the transplantation medicine area. The signal transduction involved in the cold-induced apoptosis is anfractuous, either mediated or modulated by reactive oxygen species (ROS), Ca2 , Fe2 and cold-relevant genes in vivo. Based on the worldwide research progress, we try to generally summarize the signal transduction and modu- lation mechanism involved in the course of cold-induced apoptosis. |
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| Keywords: | cold apoptosis reactive oxygen species modulation signal transduction |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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