OSCILLATION OF BLOOD MONOCYTE COUNTS IN HEALTHY INDIVIDUALS |
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| Authors: | Gerhard Meuret Christel Bremer Joachim Bammert Jörg Ewen |
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| Institution: | Department of Haematology and Oncology, Kantonsspital, St. Gallen, Switzerland;Department of Medical Statistics, University of Freiburg (Breisgau), Germany |
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| Abstract: | Daily examinations of monocyte blood counts in healthy individuals indicated the presence of a monocyte cycle. The cycle length was between 3 and 6 days. The predominant period was 5 days. A similar oscillation frequency resulted from a computer simulation of a feedback loop which linked the blood monocyte compartment (controlled variable) to the stem cell differentiation rate (controlling variable). |
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