Accurate and robust phylogeny estimation based on profile distances: a study of the Chlorophyceae (Chlorophyta)期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Accurate and robust phylogeny estimation based on profile distances: a study of the Chlorophyceae (Chlorophyta)

Authors:	Tobias?Müller author-information" > author-information__contact u-icon-before" > mailto:tobias.mueller@biozentrum.uni-wuerzburg.de" title=" tobias.mueller@biozentrum.uni-wuerzburg.de" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Sven?Rahmann,Thomas?Dandekar,Matthias?Wolf

Affiliation:	1.Department of Bioinformatics, Biocenter,University of Würzburg, Am Hubland,Würzburg,Germany;2.Department of Computational Molecular Biology,Max Planck Institute for Molecular Genetics,Berlin,Germany;3.Department of Mathematics and Computer Science,Free University of Berlin,Berlin,Germany;4.Genome Informatics, Faculty of Technology,University of Bielefeld,Bielefeld,Germany

Abstract:	Background In phylogenetic analysis we face the problem that several subclade topologies are known or easily inferred and well supported by bootstrap analysis, but basal branching patterns cannot be unambiguously estimated by the usual methods (maximum parsimony (MP), neighbor-joining (NJ), or maximum likelihood (ML)), nor are they well supported. We represent each subclade by a sequence profile and estimate evolutionary distances between profiles to obtain a matrix of distances between subclades.

Keywords:
本文献已被 SpringerLink 等数据库收录！