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替吉奥治疗结肠癌的研究
引用本文:吴元玉,范恩学,宋佳,王率,贾国梁.替吉奥治疗结肠癌的研究[J].现代生物医学进展,2014,14(1):102-103.
作者姓名:吴元玉  范恩学  宋佳  王率  贾国梁
作者单位:吉林大学第二医院 乳山市人民医院
摘    要:目的:探讨替吉奥治疗结肠癌的疗效。方法:75例经病理组织学确诊的结肠癌患者,分为A、B、C组。A组:替吉奥联合奥沙利铂(艾恒)25例。B组:5-Fu/LV联合奥沙利铂(艾恒)25例。C组:替吉奥单药治疗25例。观察疗效、疾病控制率及不良反应。结果:A组、C组与B组对比,不良反应发生率明显降低。A组有效率48%,疾病控制率88%。B组有效率28%,疾病控制率84%。C组有效率32%,疾病控制率80%。结论:替吉奥是结肠癌辅助化疗联合用药及单药治疗老年结直肠癌较好的治疗药物。

关 键 词:替吉奥  奥沙利铂  5氟尿嘧啶  结肠癌

Tegafur Capsules for Colon Cancer Research Progress
WU Yuan-yu,FAN En-xue,SONG Ji,WANG Shuai,JIA Guo-liang.Tegafur Capsules for Colon Cancer Research Progress[J].Progress in Modern Biomedicine,2014,14(1):102-103.
Authors:WU Yuan-yu  FAN En-xue  SONG Ji  WANG Shuai  JIA Guo-liang
Abstract:Objective: To investigate the efficacy of tegafur capsules for colon cancer. Methods:Seventy-five cases of colon cancer confirmed by pathology were included. The patients in group A ( n = 25) received tegafur capsules plus oxaliplatin, while those in group B ( n =25) were treated with 5-Fu /LV plus oxaliplatin. The patients in groupC ( n = 25) received tegafur capsules monotherapy for colon cancer.Results:The side effects decreased significantly in group A and C than that in B. The effective rates was 48%, 28% and 32% in group A, B and C. And the disease control rate was 88%, 84% and 80% in group A, B and C. Conclusion:Tegafur capsules is better for colon cancer in new adjuvant chemotherapy or Adjuvant Chemotherapy after Radical Surgery. Tegafur capsules monotherapy treatment older colon cancer curative effect is accurate.
Keywords:Tegafur capsules  Oxaliplatin  5-fluorouracil  Colon cancer
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