Motifs and cis-regulatory modules mediating the expression of genes co-expressed in presynaptic neurons |
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Authors: | Rui Liu Sridhar Hannenhalli Maja Bucan |
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Affiliation: | (1) Department of Genetics and Penn Center for Bioinformatics, University of Pennsylvania, Philadelphia, PA 19104, USA |
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Abstract: | Background Hundreds of proteins modulate neurotransmitter release and synaptic plasticity during neuronal development and in response to synaptic activity. The expression of genes in the pre- and post-synaptic neurons is under stringent spatio-temporal control, but the mechanism underlying the neuronal expression of these genes remains largely unknown. |
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