| EB病毒及其疫苗的研究进展 |
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| 引用本文： | 胡蓉,刘志敏. EB病毒及其疫苗的研究进展[J]. 生物技术通讯, 2004, 15(6): 611-613 |
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| 作者姓名： | 胡蓉 刘志敏 |
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| 作者单位： | 军事医学科学院,生物工程研究所,北京,100071 |
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| 摘 要： | EB病毒广泛存在于人群中，它的潜伏感染与多种疾病密切相关，包括鼻咽癌等恶性肿瘤，研制疫苗用于EB病毒相关疾病的预防和治疗十分必要。本综述了EB病毒的结构及基因表达特点、EB病毒潜伏期感染基因表达及潜伏期基因产物的功能，以及研制EB病毒疫苗的靶抗原的选择。
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| 关 键 词： | EB病毒 疫苗 基因表达 靶抗原 预防和治疗 潜伏感染 相关疾病 选择 潜伏期 基因产物 |
| 文章编号： | 1009-0002(2004)06-0611-03 |
| 修稿时间： | 2004-05-09 |
New progress in research on Epstein-Barr virus and its vaccine |
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| HU Rong,LIU Zhi-minInstitute of Biotechnology,Academy of Military Medical Sciences,Beijing ,China. New progress in research on Epstein-Barr virus and its vaccine[J]. Letters in Biotechnology, 2004, 15(6): 611-613 |
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| Authors: | HU Rong LIU Zhi-minInstitute of Biotechnology Academy of Military Medical Sciences Beijing China |
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| Affiliation: | HU Rong,LIU Zhi-minInstitute of Biotechnology,Academy of Military Medical Sciences,Beijing 100071,China |
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| Abstract: | Epstein-Barr virus (EBV) ubiquitiously exists in populations, its latent infection is closely associated with many dieases including nasopharyngeal carcinoma(NPC) and other malignancies. It is very necessary to develop a vaccine to prevent and treat these Epstein-Barr virus associated dieases. This review will focus on the structure and gene expressed character of Epstein-Barr virus. The gene expression of Epstein-Barr virus in latency infection and the function of latent cycle gene product. And the choice of target antigen in the development of EBV vaccine. |
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| Keywords: | Epstein-Barr virus vaccine target antigen |
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