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Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool
Authors:Jianing Fu  Julien Zuber  Mercedes Martinez  Brittany Shonts  Aleksandar Obradovic  Hui Wang  Sai-ping Lau  Amy Xia  Elizabeth E. Waffarn  Kristjana Frangaj  Thomas M. Savage  Michael T. Simpson  Suxiao Yang  Xinzheng V. Guo  Michelle Miron  Takashi Senda  Kortney Rogers  Adeeb Rahman  Megan Sykes
Affiliation:1. Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY 10032, USA;2. Department of Pediatrics, Columbia University, New York, NY 10032, USA;3. Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA;4. Department of Microbiology & Immunology, Columbia University, New York, NY 10032, USA;5. Department of Surgery, Columbia University, New York, NY 10032, USA;6. Center for Computational Biology and Bioinformatics, Department of Systems Biology, Columbia University, New York, NY 10032, USA
Abstract:
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  • Keywords:intestinal transplantation  intestinal allograft  hematopoietic stem cell  hematopoietic progenitor cell  mixed chimerism  immune tolerance  recent thymic immigrants  T cell receptor  recipient repopulation  circulating pool
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