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UV-Irradiated SV40 minichromosomes as substrates for DNA repair endonucleases
Authors:Dag Helland  Hans Krokan
Affiliation:1. Department of Biochemistry, University of Bergen, Bergen, Norway;2. Insitute of Medical Biology, University of Tromsø, Tromsø, Norway
Abstract:UV-irradiated SV40 minichromosomes have been shown to be a substrate for a purified DNA repair endonuclease. A UV-repair endonuclease activity was also found to be associated with the isolated SV40 minichromosomes themselves. It appeared to have similar properties to the enzymes described from other mammalian sources.
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