Sequence homology of bacterial and mitochondrial cytochrome c oxidases: Partial sequence data of cytochrome c oxidase from |
| |
Authors: | Guy CM Steffens Gerhard Buse Wolfgang Oppliger Bernd Ludwig |
| |
Institution: | 1. Abteilung Physiologische Chemie der RWTH Aachen, Aachen Federal Republic of Germany;2. Biozentrum der Universität Basel, Basel, Switzerland |
| |
Abstract: | The aerobic electron transport chain of is very similar to that of mitochondria. It has therefore been suggested that this bacterium might be evolutionarily related to mitochondria. The two subunits (Mr 45.000 and 28.000) of the cytochrome c oxidase were isolated and partially sequenced. The sequences were found to be surprisingly homologous to sequences of the subunits I and II of mitochondrial cytochrome c oxidases. The data provide a molecular basis for the symbiotic origin of mitochondria and strongly support the notion that in eucaryotic oxidases subunits I and/or II carry the redox centers, heme and copper. |
| |
Keywords: | To whom correspondence should be addressed |
本文献已被 ScienceDirect 等数据库收录! |