Variant specific surface antigens from : Chemical and physical studies |
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Authors: | G Duvillier JP Aubert T Baltz C Richet P Degand |
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Institution: | 3. Laboratoire d''Immunologie et Biologie Parasitaire, Université Bordeaux II, 146 rue Léo Saignat, 33076 Bordeaux Cédex France |
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Abstract: | Nine variant specific surface antigens were purified from clones of and characterized by amino acid analysis, isoelectric focusing and circular dichroism. The molecules showed extensive differences in their isoelectric points, and by comparison with the corresponding amino acid compositions, this variation seemed to be due to different amide contents. Circular dichroism data allowed one to divide the molecules into 4 groups according to their respective percentages inα-helical and β-sheet structure. |
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Keywords: | Botat Bordeaux Trypanozoon-antigenic type VSSA Variant Specific Surface Antigen |
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