Influence of fluoride on the uptake of 51Cr-chromate by human erythrocytes. |
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Authors: | R I Holland |
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Institution: | Department of Microbiology, Dental Faculty, University of Oslo, Norway |
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Abstract: | Uptake of 51Cr-chromate by freshly collected human erythrocytes was inhibited by 90 mM sodium fluoride only in cells preincubated with fluoride. In vitro storage also increased the sensitivity of the cells: 90 mM NaF clearly inhibited the uptake of chromate in cells stored in vitro for 5 weeks. Gel chromatography revealed two forms of 51Cr within the cells, one of small molecular weight, which thin layer chromatography indicated was unchanged chromate; the other form was apparently bound to macromolecules such as hemoglobin. |
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Keywords: | Address reprint requests to: Roy I Holland NIOM Scandinavian Institute of Dental Materials Forskningsveien 1 Oslo 3 Norway |
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