| 基于生物信息学的SNP候选位点搜寻方法 |
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| 引用本文： | 陈炜,张戈,张思仲CHEN Wei,ZHANG Ge,ZHANG Si-zhong. 基于生物信息学的SNP候选位点搜寻方法[J]. 遗传, 2001, 23(2): 153-244 |
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| 作者姓名： | 陈炜 张戈 张思仲CHEN Wei ZHANG Ge ZHANG Si-zhong |
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| 作者单位： | 华西医科大学附属第一医院医学遗传研究室，成都 610041Department of Medical Genetics,The First Affiliated Hospital,West China University of Medical Sciences,Chengdu 610041, China |
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| 摘 要： | 单核苷酸多态性(Single Nucleotide Polymorphism,SNP)是人类基因组中最常见的遗传多态，在遗传学研究的很多方面具有重要的作用。它的搜寻正受到广泛关注。近年来，国际上出现了一种基于生物信息学的发掘SNP新方法。本文对该方法的两种策略及其各自所存在的问题作一介绍。Abstract：Single Nucleotide Polymorphism (SNP), the most common form of human genetic variation, represents a valuable resources for a variety of genetic research. There is considerable interest in the discovery of it. Recently, a new method based on bioinfomatics has been developed for the discovery of SNP. In this paper, the two strategy of this method and their respective problem are discussed.
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| 关 键 词： | 生物信息学 Keywords Single Nucleotide Polymorphism (SNP) bioinformatics SNP) 单核苷酸多态性(Single Nucleotide Polymorphism |
Discovery of Candidate SNP by Bioinformatic Methods |
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| CHEN Wei,ZHANG Ge,ZHANG Si-zhong. Discovery of Candidate SNP by Bioinformatic Methods[J]. Hereditas, 2001, 23(2): 153-244 |
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| Authors: | CHEN Wei ZHANG Ge ZHANG Si-zhong |
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