Lanthionine as an essential constituent of cell wall peptidoglycan ofFusobacterium nucleatum |
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| Authors: | Keijiro Kato Toshio Umemoto Hirosuke Sagawa Shozo Kotani |
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| Institution: | (1) Department of Microbiology and Oral Bacteriology, Osaka Univesity Dental School, 4-3-48, Nakanoshima, Kita-ku, 530 Osaka, Japan;(2) Department of Bacteriology, Osaka Dental University, 1-47 Kyobashi, Higashi-ku, 540 Osaka, Japan |
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| Abstract: | Lanthionine, a sulfur-containing diamino acid which had not previously been reported as one of the main amino acids of any
bacterial cell wall peptidoglycan, was demonstrated inFusobacterium nucleatum peptidoglycan isolated by sodium dodecyl sulfate extraction and protease digestion. Lysine, diaminopimelic acid, and ornithine
were absent. Lanthionine seems to be an essential dibasic amino acid, involved in cross-linkages betwen stem peptide subunits
inF. nucleatum. |
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