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Glycerokinase activity and lipolysis regulation in brown adipose tissue of cold acclimated rats.
Authors:R Bertin
Institution:Laboratoire d''Adaptation Energétique à l''Environnement (Ecole Pratique des Hautes Etudes), Collège de France, 11, Place Marcelin Berthelot 75231 Paris Cedex 05, France
Abstract:Glycerol release by brown adipocytes from constant cold adapted rats was not stimulated by norepinephrine. On the contrary, the release was stimulated in rats adapted to a nycthemeral fluctuatiing temperature from 5 degrees to 28 degrees C. Glycerokinase activity was greatly increased in brown adipose tissue by cold adptation ; there was no change in the liver. However this increased activity cannot entirely explain the lack of norepinephrine stimulation of glycerol release in the brown adipose tissue of cold adapted rats.
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