Eosinophilic meningitis — an immunophenotyping recording of a very rare clinical entity — <Emphasis Type="Italic">Brief Report</Emphasis> |
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| Authors: | P Adam O Sobek M Hybel’ová D Dole?il J Kasík L Hajduková D Adam J Svatoňová |
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| Institution: | (1) Laboratory for CSF and Neuroimmunology, Central Military Hospital Complex, Prague, Czech Republic;(2) Department of Neurology, 3rd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic;(3) Department of Neurology, Central Military Hospital, Prague, Czechia;(4) Topelex Ltd., Central Military Hospital Complex - F1 Pavilion, U Vojenské nemocnice 1200, 162 00 Prague 6, Czech Republic |
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| Abstract: | A very rare clinical entity, so-called eosinophilic meningitis, classified by prevalence of eosinophils in cerebrospinal fluid
(CSF), with the presence of pleiocytosis, has been recorded in our laboratory four times only in the last 24 years. A low
glucose level, elevation of total protein and lactic acid in CSF were detected in all the clinical cases. The last two cases
were made possible by using flow cytometry method; surprisingly, the presence was found in mature T-cells in CSF, predominantly
helpers (CD3+, CD4+) and, practically, none is B-cells (CD19+), plasma cells (CD138+) and NK-cells. |
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