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空肠弯曲杆菌生物膜形成和调控机理研究进展北大核心CSCD
引用本文:吴清平,钟显,张菊梅. 空肠弯曲杆菌生物膜形成和调控机理研究进展北大核心CSCD[J]. 微生物学报, 2016, 56(2): 180-187
作者姓名:吴清平  钟显  张菊梅
作者单位:广东省微生物研究所, 省部共建华南应用微生物国家重点实验室, 广东省菌种保藏与应用重点实验室, 广东省微生物应用新技术公共实验室, 广东 广州 510070,广东省微生物研究所, 省部共建华南应用微生物国家重点实验室, 广东省菌种保藏与应用重点实验室, 广东省微生物应用新技术公共实验室, 广东 广州 510070;广东工业大学轻工化工学院, 化学工程专业, 广东 广州 510006,广东省微生物研究所, 省部共建华南应用微生物国家重点实验室, 广东省菌种保藏与应用重点实验室, 广东省微生物应用新技术公共实验室, 广东 广州 510070
基金项目:粤港关键领域突破项目(2011A011303001);广东省科技计划项目(2012B050800007)
摘    要:空肠弯曲杆菌(Campylobacter jejuni)分泌胞外多糖和各种胞外蛋白和核酸等相互交联在一起构成生物膜,可增强其在不利环境下的生存率,尤其是对各种洗涤剂、抗生素和消毒剂的耐受力。本文从介质表面性质、温度、气体环境、以及基因的调控等多方面阐述了空肠弯曲杆菌生物膜结构及形成调控机制,同时对各种去除生物膜的实际应用做了分析和展望,为探寻生物膜的控制方法提供参考。

关 键 词:空肠弯曲杆菌  生物膜  调控机制
收稿时间:2015-05-26
修稿时间:2015-07-08

Research progress in biofilm formation and regulatory mechanism of Campylobacter jejuni
Qingping Wu,Xian Zhong and Jumei Zhang. Research progress in biofilm formation and regulatory mechanism of Campylobacter jejuni[J]. Acta microbiologica Sinica, 2016, 56(2): 180-187
Authors:Qingping Wu  Xian Zhong  Jumei Zhang
Affiliation:State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangdong Institute of Microbiology, Guangzhou 510070, Guangdong Province, China,State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangdong Institute of Microbiology, Guangzhou 510070, Guangdong Province, China;Department of Chemical Engineering, School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, Guangdong Province, China and State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangdong Institute of Microbiology, Guangzhou 510070, Guangdong Province, China
Abstract:Biofilm of Campylobacter jejuni was formed by cross-linking its extracellular secretion, polysaccharides, various extracellular proteins, nucleic acids etc to enhance its survival in hostile environments, especially for detergents, antibiotics and disinfectants. This paper elaborated C. jejuni biofilm formation and regulation mechanisms in the surface properties of the media, temperatures, gas environment, the regulation of gene etc, also analysed and discussed a variety of biofilm removal practical applications. We hope it can provide a reference for studies on biofilm control of C. jejuni.
Keywords:Campylobacter jejuni  biofilm  regulatory mechanism
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