肥胖基因的研究进展

肥胖机制的研究是目前最为活跃并取得迅速进展的领域之一。在最近的短短两年多时间里,完成了克隆肥胖基因（ｏｂｅｓｅ ｇｅｎｅ,ｏｂ ｇｅｎｅ）、阐明ｏｂ基因产物－－ｌｅｐｔｉｎ（瘦因子）的结构、克隆ｌｅｐｔｉｎ受体的基因部分阐明ｌｅｐｔｉｎ作用的机制,使肥胖研究跨入分子时代,为人类从根本上控制体重、提高健康水平,展现了诱人的前景。本文综述几个方面的最新进展。

Progress in the study of obesity gene

The study of obesity is one of the most active and fast moving area in the basic biomedical research. In the past three years, scientists had cloned the obese gene, clarified the structure of leptin, nailed down and cloned the gene of leptin receptor, partly revealed the mechanisms of leptin's effects which make the study of obesity entering the molecular age. It shows an attractive perspective for human being to control the body weight and increase the health level. The recent progress of all these aspects is discussed in this review.