Synthesis and antifungal activity of 2,5-disubstituted-6-arylamino-4,7-benzimidazolediones |
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| Authors: | -Ryu Chung-Kyu Song Eun Ha Shim Ju-Yeon You Hea-Jung Choi Ko Un Choi Ik Hwa Lee Eun Young Chae Mi Jin |
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| Institution: | College of Pharmacy, Ewha Womans University, Seodaemun-ku, Seoul 120-750, South Korea. ckryu@mm.ewha.ac.kr |
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| Abstract: | 2,5-Disubstituted-6-arylamino-4,7-benzimidazolediones were synthesized and tested for in vitro antifungal activity against pathogenic fungi. Among them, 6-arylamino-5-chloro-2-(2-pyridyl)-4,7-benzimidazolediones exhibited potent antifungal activity against Candida species and Aspergillus niger. |
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