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Lipid peroxidation: control of cell proliferation, cell differentiation and cell death
Authors:Barrera Giuseppina  Pizzimenti Stefania  Dianzani Mario Umberto
Affiliation:Dipartimento di Medicina e Oncologia Sperimentale, Corso Raffaello 30, Torino, Italy.
Abstract:In recent years, it has become evident that lipid peroxidation is not only a mechanism for deterioration of alimentary oils and fats, but can occur even in living cells, both in pathological and physiological conditions. Through its aldehydic products, it can regulate several cellular processes, as proliferation, differentiation and apoptosis of normal and neoplastic cells. In this review we describe some recent findings obtained in these fields.
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