| 猴头菌培养物化学成分研究 |
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| 引用本文： | 喻凯,李光,李福双,徐康平,何述金,谭桂山. 猴头菌培养物化学成分研究[J]. 菌物研究, 2014, 0(2): 111-114,118 |
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| 作者姓名： | 喻凯 李光 李福双 徐康平 何述金 谭桂山 |
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| 作者单位： | [1]中南大学药学院,长沙410013 [2]中南大学附属湘雅医院,长沙410008 [3]湖南新汇制药有限公司,长沙410200 |
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| 基金项目： | 湖南省科技厅科技计划项目[（2012）42号],长沙市科技重大专项（k1204051-31） |
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| 摘 要： | 为研究猴头菌培养物的化学成分,利用硅胶柱色谱、Sephadex LH-20柱色谱、重结晶等分离技术进行系统的分离纯化,根据理化性质及光谱数据鉴定结构。结果从猴头菌固体培养物中共分离得到10个化合物,分别为大黄酚、大黄素甲醚、大黄素、芦荟大黄素、大黄酸、麦角甾醇、β-谷甾醇、5α-豆甾-3,6-二酮、麦角甾醇过氧化物、3-吲哚甲醛。其中化合物15,8,10均为首次从猴头菌培养物中分离得到。
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| 关 键 词： | 猴头菌 培养物 化学成分 |
Study on Chemical Constituents of Hericium erinaceus Culture |
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| YU Kai,LI Guang,LI Fu-shuang,XU Kang-ping,HE Shu-jin,TAN Gui-shan. Study on Chemical Constituents of Hericium erinaceus Culture[J]. Journal of Fungal Research, 2014, 0(2): 111-114,118 |
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| Authors: | YU Kai LI Guang LI Fu-shuang XU Kang-ping HE Shu-jin TAN Gui-shan |
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| Affiliation: | 1. School of Pharmaceutical Sciences, Central South University, Changsha 41 0013, China ; 2. Xian- gya Hospital, Central South University, Changsha 410008, China; 3 , Hunan Xinhui Pharmaceuti- cal Co., Ltd., Chansha 410200,China) |
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| Abstract: | In order to study the chemical constituents of Hericium erinaceus culture, the compounds were isolated and purified by column chromatography over silicagel, Sephadex LH-20 and recrystalli- zation. Their structures were identified on the basis of their physicochemical properties and spectro- scopic analysis. The results showed that 10 compounds were isolated and identified as follows： chry- sophanol, physcion, emodin, aloeemodin, rhein, ergosterol, sitosterol, 5α-stigmasta-3,6-dione, er- gosterol peroxide and indole-3-earboxaldehyde. Compounds 1 to 5, 8, 10 have been isolated from the culture of Hericium erinaceus for the first time. |
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| Keywords: | Hericium erinaceus culture chemical constituent |
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