Mechanical characteristics of synthetic polyelectrolyte gel as a physical model of the cytoskeleton |
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| Authors: | T F Shklyar O A Toropova A P Safronov G H Pollack F A Blyakhman |
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| Institution: | 1.Urals State Medical Academy,Yekaterinburg,Russia;2.Urals State University,Yekaterinburg,Russia;3.University of Washington,Seattle,USA |
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| Abstract: | A physical model of the cytoskeleton based on synthetic polyelectrolyte hydrogel of polymethacrylic acid has been proposed.
From the physicochemical point of view, the structures of polyelectrolyte gel and the cytoskeleton show a high degree of similarity.
It has been shown that polyelectrolyte gel can shorten and produce mechanical stress in response to changes in the composition
of the surrounding solution. The mechanical properties of the model gel have been evaluated: Young modulus (2–6 kPa), stress
relaxation time (0.1–1 s), and apparent viscosity (0.3–3 kPa s). The viscoelastic properties of the gel depend on the degree
of its swelling. It has been demonstrated that the mechanical properties of gels of polymethacrylic acid are close to those
of biological objects. |
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