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The sequence of a human mitochondrial glycerol-3-phosphate dehydrogenase-encoding cDNA |
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| Authors: | Donald A. Lehn Laura J. Brown Gregg D. Simonson Susan M. Moran Michael J. MacDonald |
| Affiliation: | University of Wisconsin Childrens Diabetes Center, Madison, WI 53706, USA |
| Abstract: | A 2618-bp cDNA that encodes the human mitochondrial glycerol-3-phosphate dehydrogenase has been isolated from a HeLa cell cDNA library and the nucleotide sequence determined. An open reading frame encodes a protein of 727 amino acids that is 96% similar to the rat protein and, like the rat protein, contains sites homologous to the Ca2+ -binding sites of calmodulin, as well as FAD- and putative glycerol-phosphate-binding sites. |
| Keywords: | Human cDNA library HeLa cell nuclear encoded amino-acid homology calcium-binding sites |
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