Engineering stem cell expansion |
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Authors: | Bernstein Irwin D Delaney Colleen |
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Institution: | Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA. lbernste@fhcrc.org |
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Abstract: | In this issue of Cell Stem Cell, Csaszar et al. (2012) develop a culture method that overcomes current limitations in ex vivo hematopoietic stem/progenitor cell expansion by continuously diluting inhibitory signaling factors and maintaining stem cell density. This approach enhances the generation of precursors with potential therapeutic utility. |
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