Phylogenetic comparative assembly |
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| Authors: | Peter Husemann and Jens Stoye |
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| Institution: | (1) AG Genominformatik, Technische Fakult?t, Bielefeld University, Germany;(2) International Graduate School in Bioinformatics and Genome Research, Bielefeld University, Germany;(3) Institute for Bioinformatics, Center for Biotechnology (CeBiTec), Bielefeld University, Germany |
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| Abstract: | Background Recent high throughput sequencing technologies are capable of generating a huge amount of data for bacterial genome sequencing
projects. Although current sequence assemblers successfully merge the overlapping reads, often several contigs remain which
cannot be assembled any further. It is still costly and time consuming to close all the gaps in order to acquire the whole
genomic sequence. |
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