Structure, assembly and reading of centromeric chromatin |
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| Authors: | Maddox Paul S Corbett Kevin D Desai Arshad |
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| Institution: | Institute for Research in Immunology and Cancer, Dept of Pathology and Cell Biology, Université de Montréal, Montréal, QC H3C 3J7, Canada. paul.maddox@umontreal.ca |
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| Abstract: | Centromeres are epigenetically defined chromatin domains marked by the presence of the histone H3 variant CENP-A. Here we review recent structural and biochemical work on CENP-A, and advances in understanding the mechanisms that propagate and read centromeric chromatin domains. |
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