RFLP analysis of SLA haplotypes in Swiss large white and American Hampshire pigs using SLA class I and class II probes |
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| Authors: | Yun‐Chao Shia Catherine Gautschi Ming‐Sheung Ling Jonathan E. Beever David G. McLaren Harris A. Lewin |
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| Affiliation: | 1. Department of Animal Sciences , University of Illinois , Urbana, Illinois;2. Division of Immunogenetics, Institute of Animal Breeding , University of Berne , Berne, Switzerland |
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| Abstract: | Summary Restriction fragment length polymorphism (RFLP) analyses of swine leukocyte antigen (SLA) class I and class II genes from Swiss Large White and American Hampshire families were performed using porcine DNA probes. Class I and class II RFLPs associated with the serologically‐defined haplotypes SLA H1, H8, H16 and H24 and with serotypes SLA 15, 16; SLA 14; and SLA 6, SB 19, were identified. Seven allelic class I RFLP patterns were observed. For genes in the SLA class II region, six allelic RFLP patterns of DQA and DQB; five allelic RFLP patterns of DRA; and seven allelic RFLP patterns of DRB were observed. The serologically‐defined H8 haplotype was subtyped based on differences in class II RFLPs. |
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