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Successful production of transgenic rats
Authors:Shin‐ichi Hochi  Takashi Ninomiya  Miho Honma  Atsushi Yuki
Institution:Research Institute of Life Science , Snow Brand Milk Products, Co., Ltd. , 519 Shimoishibashi, Ishibashi‐machi, Shimotsuga‐gun, Tochigi, 329‐05, Japan
Abstract:Abstract

DNA of pSV2‐gpt‐gE1A or SV2‐cat microinjected into pronuclei of fertilized rat eggs was found incorporated into chromosomes of 3 out of 48 (6.3%) or 10 out of 66 (15.2%) new born rats, respectively. The transgenic rats carrying SV2‐cat DNA transmitted the transgenes to their G1 progeny.
Keywords:Myogenic expression  DNA vector  GHRH  Bupivacaine  Growth  Sheep
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