Research Institute of Life Science , Snow Brand Milk Products, Co., Ltd. , 519 Shimoishibashi, Ishibashi‐machi, Shimotsuga‐gun, Tochigi, 329‐05, Japan
Abstract:
Abstract DNA of pSV2‐gpt‐gE1A or SV2‐cat microinjected into pronuclei of fertilized rat eggs was found incorporated into chromosomes of 3 out of 48 (6.3%) or 10 out of 66 (15.2%) new born rats, respectively. The transgenic rats carrying SV2‐cat DNA transmitted the transgenes to their G1 progeny.