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Mechanism of antioxidant protection of an organism from oxidative stress
Authors:Shapoval G S  Gromovaia V F
Affiliation:Institute of Bioorganic Chemistry and Petroleum Chemistry, National Academy of Sciences of Ukraine, Kyiv.
Abstract:The analysis of the literature and authors' data concerning the mechanism of antioxidant protection of the organism under conditions of "oxygen stress" is submitted. Possible mechanisms of initiation of free radical reactions with participation of oxygen and the role of hydroxyl radicals, being one of the basic factors, determining toxic action of oxygen, are considered. The methods of estimation of antiradical activity of biologically active compounds are characterized.
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