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FAF1 downregulation by Toxoplasma gondii enables host IRF3 mobilization and promotes parasite growth
Authors:Fei-Fei Gao  Juan-Hua Quan  In-Wook Choi  Yeon-Jae Lee  Seul-Gi Jang  Jae-Min Yuk  Young-Ha Lee  Guang-Ho Cha
Affiliation:1. Brain Korea 21 FOUR Project for Medical Science, Chungnam National University, Daejeon, Korea

Department of Medical Science and Department of Infection Biology, Chungnam National University, Daejeon, Korea

Contribution: Conceptualization (lead), Data curation (lead), Formal analysis (equal), ​Investigation (equal), Methodology (lead), Project administration (lead), Resources (equal), Software (equal), Validation (equal), Writing - original draft (supporting);2. Department of Gastroenterology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China

Contribution: Conceptualization (lead), Data curation (equal), Formal analysis (lead), Funding acquisition (equal), ​Investigation (equal), Methodology (lead), Project administration (equal), Resources (equal), Software (lead), Supervision (equal), Visualization (lead), Writing - original draft (supporting);3. Department of Medical Science and Department of Infection Biology, Chungnam National University, Daejeon, Korea

Contribution: Methodology (equal), Project administration (equal), Resources (equal), Validation (equal);4. Brain Korea 21 FOUR Project for Medical Science, Chungnam National University, Daejeon, Korea

Department of Medical Science and Department of Infection Biology, Chungnam National University, Daejeon, Korea

Contribution: Methodology (equal), Project administration (equal), Resources (equal);5. Brain Korea 21 FOUR Project for Medical Science, Chungnam National University, Daejeon, Korea

Department of Medical Science and Department of Infection Biology, Chungnam National University, Daejeon, Korea

Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), ​Investigation (equal), Supervision (equal);6. Brain Korea 21 FOUR Project for Medical Science, Chungnam National University, Daejeon, Korea;7. Department of Medical Science and Department of Infection Biology, Chungnam National University, Daejeon, Korea

Abstract:
Keywords:AKT  ARPE-19 cells  FAF1  IRF3  Toxoplasma gondii
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