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Lipotoxicity suppresses the synthesis of growth hormone in pituitary somatotrophs via endoplasmic reticulum stress |
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| Authors: | Ying Gong Jianmei Yang Shuoshuo Wei Rui Yang Ling Gao Shanshan Shao Jiajun Zhao |
| Affiliation: | 1. Department of Endocrinology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, China Shandong Institute of Endocrine and Metabolic Disease, Jinan, China Contribution: Data curation (lead), Formal analysis (lead), Investigation (lead);2. Department of Pediatric Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China Contribution: Data curation (supporting), Formal analysis (supporting), Investigation (supporting);3. Department of Endocrinology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, China Shandong Institute of Endocrine and Metabolic Disease, Jinan, China Contribution: Data curation (supporting), Investigation (supporting);4. Experimental Animal Center, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China Contribution: Data curation (supporting), Investigation (supporting);5. Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, China;6. Department of Endocrinology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China |
| Abstract: | |
| Keywords: | anterior pituitary endoplasmic reticulum stress growth hormone high-fat diet lipotoxicity Pit-1 |