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Imipramine impedes glioma progression by inhibiting YAP as a Hippo pathway independent manner and synergizes with temozolomide |
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| Authors: | Yan Wang Xiang Wang Xu Wang Di Wu Ji Qi Yu Zhang Kai Wang Ding Zhou Qing-Ming Meng Er Nie Qiang Wang Ru-Tong Yu Xiu-Ping Zhou |
| Institution: | 1. Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China
Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China Contribution: Conceptualization (lead), Data curation (lead), Formal analysis (lead), Writing - original draft (lead);2. Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China Contribution: Data curation (equal), Formal analysis (equal), ?Investigation (equal), Writing - original draft (supporting);3. Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China Contribution: Data curation (supporting), Formal analysis (supporting), ?Investigation (equal);4. Pathological Diagnosis Center, Xuzhou Central Hospital, Xuzhou, China;5. Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China Contribution: Data curation (supporting), ?Investigation (equal), Visualization (equal);6. Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China Contribution: Conceptualization (supporting), ?Investigation (supporting), Validation (supporting);7. Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China Contribution: Data curation (supporting), ?Investigation (supporting), Validation (supporting);8. Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China Contribution: Conceptualization (supporting), Resources (supporting), Visualization (supporting);9. Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China Contribution: ?Investigation (supporting), Validation (supporting);10. Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China Contribution: Conceptualization (supporting), Methodology (lead), Validation (supporting);11. Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China Contribution: Methodology (supporting), Software (supporting);12. Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China |
| Abstract: | |
| Keywords: | glioma imipramine proliferation temozolomide YAP |