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MicroRNA-205-5p targets E2F1 to promote autophagy and inhibit pulmonary fibrosis in silicosis through impairing SKP2-mediated Beclin1 ubiquitination |
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| Authors: | Qingzeng Qian Qinghua Ma Bin Wang Qingqiang Qian Changsong Zhao Fumin Feng Xiaona Dong |
| Institution: | 1. School of Public Health, North China University of Science and Technology, Tangshan, China
Contribution: Conceptualization (equal);2. Department of Preventive Health, The Third People’s Hospital of Xiangcheng District in Suzhou, Suzhou, China Contribution: Data curation (equal);3. Department of Pediatrics, North China University of Science and Technology Affiliated Hospital, Tangshan, China Contribution: Formal analysis (equal);4. Department of Neurology, Tangshan Gongren Hospital, Tangshan, China Contribution: Funding acquisition (equal);5. Department of Emergency, Tangshan Hospital of Traditional Chinese Medicine, Tangshan, China Contribution: Formal analysis (equal);6. School of Public Health, North China University of Science and Technology, Tangshan, China Contribution: Validation (equal);7. Department of Respiratory Medicine, Tangshan People's Hospital, Tangshan, China |
| Abstract: | |
| Keywords: | Beclin1 ubiquitination E2F1 macrophage autophagy MicroRNA-205-5p pulmonary fibrosis silicosis SKP2 |