| 一氧化氮合酶的遗传、生理研究进展 |
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| 引用本文： | 邵韵平. 一氧化氮合酶的遗传、生理研究进展[J]. 生物学杂志, 2011, 28(5): 77-78,90. DOI: 10.3969/j.issn.2095-1736.2011.05.077 |
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| 作者姓名： | 邵韵平 |
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| 作者单位： | 无锡卫生高等职业技术学校,江苏,无锡,214028 |
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| 摘 要： | 一氧化氮具有广泛的生理功能,哺乳动物体内的NO是由NO合酶(NOS)氧化L-精氨酸而合成的,合成后的NO迅速跨膜扩散释放,NO合成失调能介导多种疾病。催化NO生物合成的NOS有三种亚型:神经元型NOS(nNOS)、内皮型NOS(eNOS)和诱导型NOS(iNOS),目前,人的三型NOS已纯化并且已分子克隆成功,对一氧化氮合酶的遗传研究确认了NOS家族的基因结构和染色体定位。
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| 关 键 词： | 一氧化氮合酶 人类NOS基因定位 NOS生理功能 |
The heredity and physiological research progress of nitric oxide synthase |
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| SHAO Yun-ping. The heredity and physiological research progress of nitric oxide synthase[J]. Journal of Biology, 2011, 28(5): 77-78,90. DOI: 10.3969/j.issn.2095-1736.2011.05.077 |
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| Authors: | SHAO Yun-ping |
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| Affiliation: | SHAO Yun-ping (Wuxi Higher Health Vocational Technology School,Wuxi 214028,China) |
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| Abstract: | Nitric oxide(NO) plays various roles in a number of physiological and pathological processes.It can be generated from L-arginine by family enzymes known as nitric oxide synthase(NOS).Synthetic NO is rapidly released across transmenbrane diffusion.Dysfunction of NO formation has been implicated in various diseases.Thereare three subtypes of NOS which catalyze nitric oxide biosynthesis,such as neuronal nitric oxide synthase(Nnos),endothelial nitric synthase(eNOS) and inducible nitric oxide synthase(iNOS).At p... |
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| Keywords: | nitric oxide synthase(NOS) NOS gene position in human beings physiological action of NOS |
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