Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging

Authors:	Hanzhi Luo Wei-Chieh Mu Rajendra Karki Hou-Hsien Chiang Mary Mohrin Jiyung J. Shin Rika Ohkubo Keisuke Ito Thirumala-Devi Kanneganti Danica Chen

Affiliation:	1. Program in Metabolic Biology, Nutritional Sciences & Toxicology, University of California, Berkeley, CA 94720, USA;2. Department of Immunology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA;3. Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA;4. Departments of Cell Biology and Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA;5. Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA

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Keywords:	SIRT2 SIRT3 SIRT7 mitochondrial UPR oxidative stress hematopoietic stem cell aging clonal hematopoiesis NLRP3 inflammasome
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