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Quantitative 3D Mapping of the Human Skeletal Muscle Mitochondrial Network
Authors:Amy E Vincent  Kathryn White  Tracey Davey  Jonathan Philips  R Todd Ogden  Conor Lawess  Charlotte Warren  Matt G Hall  Yi Shiau Ng  Gavin Falkous  Thomas Holden  David Deehan  Robert W Taylor  Doug M Turnbull  Martin Picard
Institution:1. Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK;2. MRC Centre for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK;3. EM Research Services, Newcastle University, Newcastle upon Tyne, UK;4. Department of Biostatistics, Columbia University Mailman School of Public Health, New York, NY, USA;5. Institute of Child Health, University College London, London, UK;6. National Physical Laboratory, Teddington, UK;7. Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK;8. Department of Psychiatry, Division of Behavioral Medicine, Columbia University Irving Medical Center, New York, NY, USA;9. Department of Neurology and Columbia Translational Neuroscience Initiative, H. Houston Merritt Center, Columbia University Irving Medical Center, New York, NY, USA;10. Columbia University Aging Center, Columbia University, New York, NY, USA
Abstract:
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  • Keywords:serial block-face SEM  reconstruction  mitochondrial disease  skeletal muscle  3D morphometry  machine learning  mitochondrion  nanotunnel  reticulum  imaging
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