Adjuvant effect ofBacillus firmus in intranasal immunization of guinea pigs with inactivated type B influenza virus |
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| Authors: | M Havlíčková L Prokešová P Zanvit J Táčner R Limberková |
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| Institution: | National Institute of Public Health, Centre of Epidemiology and Microbiology, 100 42 Prague, Czechia. nflucprg@szu.cz |
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| Abstract: | Intranasal immunization of guinea pigs with inactivated type B influenza virus plus inactivated Bacillus firmus as an adjuvant compared to the virus alone yields higher titers of serum hemagglutination-inhibiting antibodies and virus-neutralizing antibodies. This phenomenon could be useful in standard serology, especially in the preparation of immune sera against highly pathogenic strains for in vitro diagnosis. |
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